Associate Director / Director of Product Management, Signatera Hematologic Oncology (Heme)

Role overview

Lead product strategy and roadmap for a personalized molecular residual disease (MRD) test used in hematologic cancers, initially multiple myeloma and lymphomas. The work spans product definition, clinical evidence, market entry, and support for clinical trials, coordinating teams across research and development, laboratory operations, software, medical, regulatory, and commercial functions.

Responsibilities - Set the roadmap for heme indications, prioritizing product needs and opportunities across multiple myeloma, lymphoma, and future malignancies. - Plan launch as a laboratory-developed test, coordinating validation, laboratory and regulatory requirements, reimbursement considerations, and operational readiness. - Define assay, sample, workflow, and reporting requirements with technical and laboratory partners. - Support clinical studies, including investigational use, trial start-up, and progression toward regulated use; coordinate with clinical, regulatory, and business development teams. - Develop product metrics and dashboards, analyze adoption and operational performance, and use findings to guide improvements. - Shape evidence generation, customer research, product positioning, and business cases; present recommendations to senior leadership.

Requirements - Bachelor’s degree in life sciences, statistics, engineering, or a related field; an advanced degree is preferred. - At least five years in product management, product marketing, or market analytics in diagnostics, biotechnology, or pharmaceuticals; seven or more is preferred. - Experience bringing a molecular test to market as a laboratory-developed test, including clinical validation and laboratory requirements. - Clinical trial experience, including work in investigational-use and in-vitro-diagnostic settings. - Knowledge of oncology molecular testing, next-generation sequencing, biomarkers, and genomic data analysis; MRD experience is preferred. - Hematologic oncology experience, especially multiple myeloma or lymphoma, is strongly preferred.

Nice to have

Experience with SQL or similar analytics tools, high-complexity molecular labs and plasma workflows, whole-genome sequencing, and variant interpretation—including structural and phased variants—is advantageous.

Benefits and work setup

The listing describes medical, dental, vision, life, and disability coverage, along with retirement, commuter, family leave, and fertility-related benefits for eligible employees.