Bioinformatics Scientist

Role overview

Provide bioinformatics, statistical, and scientific computing support to researchers working with high-throughput genomic and related data. The work spans consultation on experimental design, complex data analysis, production workflow development, and collaboration on research publications and scalable analytical resources.

Responsibilities

- Advise researchers on statistical design for genome-scale experiments, data mining, and scientific analysis. - Analyze somatic and germline variants, single-cell and bulk expression data, genome and transcriptome assemblies, comparative genomics, proteomics, ChIP-seq, and ATAC-seq data. - Build and maintain high-throughput pipelines for these data types and provide programming and troubleshooting support. - Analyze genomic and clinical research data and support statistical interpretation and experimental design. - Help develop scalable resources for sequencing, structural biology, computational, and machine learning analyses. - Contribute to scientific publications and create technical and user documentation for tools and workflows.

Requirements

- Bachelor’s degree in a related field; a master’s or doctorate is preferred. - At least four years of bioinformatics experience, including two or more years developing and maintaining production pipelines. - Expert-level skill in at least two of Python, R, C/C++, or shell scripting. - Experience building container images with Docker, Podman, or Singularity/Apptainer, and expertise in a workflow framework such as Snakemake, Nextflow, CWL, or WDL. - Experience developing pipelines on local high-performance computing infrastructure, plus strong skills in next-generation sequencing analysis, statistical modeling, scripting, and biological interpretation. - Ability to obtain and maintain a Public Trust security clearance.

Nice to have

- Experience deploying pipelines or applications in AWS, Google Cloud, or Azure; application development with Django, Flask, R Shiny, Electron, Flutter, or React; or work in a laboratory setting.

Benefits and work setup

- The role is based in Bethesda, Maryland, supporting research teams at a federal biomedical research institute. - The listed salary range is USD 120,000–130,000. - Benefits include employee medical, dental, and vision coverage; paid time off and holidays; a 401(k) match up to 5%; education support; and flexible spending and transportation reimbursement accounts.